Third M.I.T. Conference on Computational Fluid and Solid Mechanics June 14–17, 2005  

Application of vascular CFD for clinical evaluation of cerebral aneurysms

M.A. Castroa, C.M. Putmanb, J.R. Cebrala,*
aSchool of Computational Sciences, George Mason University, Fairfax, VA 22030, USA bInterventional Neuroradiology, Inova Fairfax Hospital, Falls Church, VA 22040, USA
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ABSTRACT
The purpose of our study was to demonstrate the feasibility of using patient-specific 3-D rotational angiography (3DRA) image data from clinical studies to construct corresponding realistic patient-specific computational fluid dynamics (CFD) models of cerebral aneurysms. Using these models, the intra-aneurysmal flow patterns are characterized and their possible associations to the clinical history of aneurysmal rupture are explored. Finally, these models are used to analyze the alterations in the flow dynamics precipitated by endovascular procedures.

Keywords:  Hemodynamics; Cerebral aneurysms; Rotational angiography; Stenting; Coiling
* Corresponding author. Tel.: +1 703 993 4078; Fax: +1 703 993 4064; E-mail: jcebral@gmu.edu